Bugatti 100P, in 1937 the development of this extremely advanced airplane was started.
Tragically the Bugatti 100P airplane never flew, the Germans invaded Paris before it was 100% ready. The airplane surprisingly survived the war, and still exists. The airplane is now in the EAA museum in Oshkosh, USA. Both engines exist, and were built into Bugatti race-cars.
For more info go to http://www.bugattiaircraft.com/plane.htm